Fallopian tube damage or blockage: Women with blocked fallopian tubes can use IVF to achieve pregnancy.
Ovulation disorders: If ovulation is infrequent or absent, fewer eggs are available for fertilization.
Impaired sperm production: IVF is also used for cases of male infertility treatment that cannot be overcome with IUI treatment or other treatments. Men with low sperm count are more likely to achieve success with IVF.
Uterine fibroids: Fibroids are common in women in the age bracket 30 to 40. Fibroids can interfere with implantation of the fertilized egg.
How does IVF work?
The timeline for IVF treatment usually follows the following path:
Ovary stimulation: For eight to 14 days near the beginning of your menstrual cycle, you take a type of fertility drug that stimulates your ovaries to develop multiple mature eggs for fertilization.
Trigger shot: When the follicles are ready, you get a ‘trigger shot’, an injection that causes the eggs to mature fully and become capable of being fertilized.
Collecting the eggs: A thin needle is inserted through the vaginal wall to remove the eggs from the follicles.
Fertilization: An embryologist will select the healthiest of the fertilized embryos if any, and your fertility doctor will decide on how many embryos to transfer.
Developing embryos: Some of the eggs that were successfully fertilized become embryos. Some of these embryos will become blastocysts with a fluid-filled cavity and tissues that are beginning to separate into placenta and baby.
Embryo selection: The embryologist selects the most viable embryo or embryos to place in the uterus.
Planting the embryos: The doctor places embryos in the uterus by inserting a thin tube (a catheter) through your cervix.
Any embryo that was not replaced on this occasion may be frozen and used the following month if conception fails to occur or at some later date if a further pregnancy is desired.
What is the success rate for IVF?
- About 1 in 4 women conceive with each treatment cycle.
- Your chance for IVF success will depend on various factors, including your age, cause(s) of your infertility, whether or not donor eggs are being used, previous treatment outcomes, and the clinic’s expertise in your particular needs.
What are the risks associated with IVF treatment?
Specific steps of an in vitro fertilization (IVF) cycle carry risks, including:
Multiple births: IVF increases the risk of multiple births if more than one embryo is implanted in your uterus.
Premature delivery and low birth weight: As per a research, IVF slightly increases the risk that a baby will be born early or with a low birth weight.
Ovarian Hyperstimulation Syndrome: Injectable fertility drugs can cause Ovarian Hyperstimulation Syndrome. OHSS occurs in 10% of women going through IVF treatment.
At, Surya Fertility Centre, the cumulative pregnancy rate is 60% which includes fresh and frozen embryos transfer.
Three main reasons for an improved success rate of IVF at Surya Fertility Centre are:
- Personalized treatment protocols
- Blastocyst culture and single embryo transfer
- Adopting segmental IVF treatment wherein fresh embryo transfer is not done if the patient’s conceiving chances are low. Frozen embryo transfer is planned at a later date in order to improve the chances of conception.
- Providing advanced fertility treatments like PGS/PGD and personalized embryo transfer with endometrial Receptivity assessment has led to improved IVF ICSI results at Surya Fertility Centre.
ICSI (Intracytoplasmic Sperm Injection)
What is ICSI?
ICSI is a modification of the IVF technique and is used in situations when a small amount of sperm is available or incase the sperm is not strong enough to cause fertilization.
How does ICSI work?
With this method, an individual sperm is selected and injected directly into an egg. This process is repeated with all available eggs.
If a female is unable to conceive/become pregnant after the first treatment, then the following course of action is followed.
If ovaries respond well, that means a reasonable number of eggs were collected and fertilized to produce good quality embryos, then there would be no contraindication to you having 3-4 cycles of IBF.
If the ovaries fail to respond even after an increased dosage of the Gonadotrophin injections or if the eggs fail to fertilize, the patient is advised to go for alternative treatments.
What are the risks associated with ICSI treatment?
- The use of Gonadotrophin injections may cause many follicles to grow. This further results in Ovarian Hyperstimulation Syndrome (OHSS).
- With OHSS, the ovaries become swollen and form cysts. The risk of severe OHSS is 2-3 per 100 women.
- In an attempt to maximize the chance of pregnancy, it is usual to replace two embryos.